Stony Brook University | School of Medicine | Health Sciences Center
Jizu Zhi, Ph.D., Research Assistant Professor.
Jizu Zhi, Ph.D.
Bioinformatician, Sr. Programmer/Analyst
Research Assistant Professor, Pathology
Stony Brook University Medical Center
HSC T8, Rm. 055
Stony Brook, NY 11794-8085
Tel: 631-444-1295
Email: jizu@osa.sunysb.edu
Education:
| 1990 | B.S., Genetics and Genetic Engineering, |
1997 | Ph.D., Molecular and Cellular Biology, |
2001 | M.S., Computer Science, Stony Brook University, New York |
Postdoctoral and Professional Training:
| 1997-2001 | Postdoctoral Fellow, Department of Biomedical Engineering, |
Research Summary:
Dr. Zhi is interested in various topics in Bioinformatics and Cheminformatics. He develops algorithms and computational tools that facilitate genomic and proteomic research. He provides a broad range of Bioinformatics/Cheminformatics services to the Stony Brook biomedical community. He also developed and maintains the School of Medicine Research Informatics database.
Selected Publications:
Zhi J, Hatchwell E. (2008) Human MLPA Probe Design (H-MAPD): a probe design tool for both electrophoresis-based and bead-coupled human multiplex ligation-dependent probe amplification assays. BMC Genomics 9:409.
Zhi J, Xu G, Rubin C, Hadjiargyrou M. (2008) The lipogenic gene Spot 14 is activated in bone by disuse, yet remains unaffected by a mechanical signal anabolic to the skeleton. Calcif Tissue Int 82:148-154.
Powers JF, Evinger MJ, Zhi J, Picard KL, Tischler AS. (2007) Pheochromocytomas in Nf1 knockout mice express a neural progenitor gene expression profile. Neuroscience 147:928-937.
Chen JJ, Zhi J, Mao W, Steinhardt GF. (2006) MrNomogram: A web-based multivariable pediatric renal nomogram. J Pediatr Urol 2:436-438.
Filkov V, Skiena S, Zhi J. (2002) Analysis techniques for microarray time-series data. J Comput Biol 9:317-330.
Sommerfeldt DW, Zhi J, Rubin CT, Hadjiargyrou M. (2002) Proline-rich transcript of the brain (prtb) is a serum-responsive gene in osteoblasts and upregulated during adhesion. J Cell Biochem 84: 301-308.
Zhi J, Sommerfeldt DW, Rubin CT, Hadjiargyrou M. (2001) Differential expression of neuroleukin in osseous tissues and its involvement in mineralization during osteoblast differentiation. J Bone Min Res 16: 1994-2004.
Zhi J, Mathew E, Freundlich M. (1999) Lrp binds to two regions in the dadAX promoter region of Escherichia coli to repress and activate transcription directly. Mol Microbiol 32: 29-40.
Zhi J, Mathew E, Freundlich M. (1998) In vitro and in vivo characterization of three major dadAX promoters in Escherichia coli regulated by cyclic AMP-CRP and Lrp. Mol General Genet 258: 442-447.
Mathew E, Zhi J, Freundlich M. (1996) Lrp is a direct repressor of the dad operon in Escherichia coli. J Bacteriol 178: 7234-7240.
