Jizu Zhi, PhD

Jizu Zhi, PhD
Bioinformatician, Sr. Programmer/Analyst
Research Assistant Professor, Pathology
Health Science Center, Level 8
Stony Brook Medicine
Stony Brook, NY 11794-8085

Tel: (631) 444-1295
Email: jizu.zhi.2@stonybrookmedicine.edu

Research Summary:
Dr. Zhi is interested in various topics in Bioinformatics and Cheminformatics. He develops algorithms and computational tools that facilitate genomic and proteomic research. He provides a broad range of Bioinformatics/Cheminformatics services to the Stony Brook biomedical community. He also developed and maintains the School of Medicine Research Informatics database.

Education:
Institution and Location	Degree	Year(s)	Field of Study
Fudan University, Shanghai, China	B.S.	1990	Genetics and Genetic Engineering
Stony Brook University, NY	Ph.D.	1997	Molecular and Cellular Biology
Stony Brook University, NY	M.S.	2001	Computer Science

Peer Reviewed Publications:
Zhi J, Hatchwell E. (2008) Human MLPA Probe Design (H-MAPD): a probe design tool for both electrophoresis-based and bead-coupled human multiplex ligation-dependent probe amplification assays. BMC Genomics 9:409.

Zhi J, Xu G, Rubin C, Hadjiargyrou M. (2008) The lipogenic gene Spot 14 is activated in bone by disuse, yet remains unaffected by a mechanical signal anabolic to the skeleton. Calcif Tissue Int 82:148-154.

Powers JF, Evinger MJ, Zhi J, Picard KL, Tischler AS. (2007) Pheochromocytomas in Nf1 knockout mice express a neural progenitor gene expression profile. Neuroscience 147:928-937.

Chen JJ, Zhi J, Mao W, Steinhardt GF. (2006) MrNomogram: A web-based multivariable pediatric renal nomogram. J Pediatr Urol 2:436-438.

Filkov V, Skiena S, Zhi J. (2002) Analysis techniques for microarray time-series data. J Comput Biol 9:317-330.

Sommerfeldt DW, Zhi J, Rubin CT, Hadjiargyrou M. (2002) Proline-rich transcript of the brain (prtb) is a serum-responsive gene in osteoblasts and upregulated during adhesion. J Cell Biochem 84: 301-308.

Zhi J, Sommerfeldt DW, Rubin CT, Hadjiargyrou M. (2001) Differential expression of neuroleukin in osseous tissues and its involvement in mineralization during osteoblast differentiation. J Bone Min Res 16: 1994-2004.

Zhi J, Mathew E, Freundlich M. (1999) Lrp binds to two regions in the dadAX promoter region of Escherichia coli to repress and activate transcription directly. Mol Microbiol 32: 29-40.

Zhi J, Mathew E, Freundlich M. (1998) In vitro and in vivo characterization of three major dadAX promoters in Escherichia coli regulated by cyclic AMP-CRP and Lrp. Mol General Genet 258: 442-447.

Mathew E, Zhi J, Freundlich M. (1996) Lrp is a direct repressor of the dad operon in Escherichia coli. J Bacteriol 178: 7234-7240.