Alexei Petrenko, Ph.D., Research Assistant Professor.

Alexei Petrenko, PhD
Senior Research Scientist
BST9, Rm 134
Stony Brook University Medical Center
State University of New York at Stony Brook
Stony Brook, NY 11794-8691

Ph: 631-444-3520
Fax:  (631) 444-3424
email: Alexei.Petrenko@stonybrook.edu

 
Education:

Appointments:

Publications in Peer-Reviewed Journals:

1) Dem’ianova NG, Zlochevskii ML, Kavsan VM, Kozlov YI, Petrenko AI.  Cloning of the fish (Oncorhynchus keta) insulin gene in Escherichia coli. [article in Russian] Dokl Akad Nauk SSSR 1981;256(4):999-1003.

2) Petrenko AI, Kavsan VM, Dobrovol’skaia GN, Kozlov YI, Sova VV.  Hybridization analysis of the correspondence of nucleotide sequences of cDNA for salmon and human insulin.  [Aticle in Russian] Dokl Akad Nauk SSSR 1981;257(2):504-505.

3) Sorokin AV, Petrenko OI, Kavsan VM, Kozlov YI, Debabov VG, Zlochevskij ML.  Nucleotide sequence analysis of the cloned salmon preproinsulin cDNA. Gene 1982 Dec;20(3):367-376

4) Kavsan VM, Petrenko AI, Ryndich AV, Dobrovol’skaia GN, Sova VV.  Synthesis, cloning and sequence determination of Siberian salmon preproinsulin cDNA. [Article in Russian] Mol Biol (Mosk) 1983 Jan;17(1):42-53.

5) Kavsan VM, Petrenko AI, Brykov VI.  Insulin-related sequences in the genomes of fish and invertebrates.  [Article in Russian] Dokl Akad Nauk SSSR 1984;274,219-221.

6) Kavsan VM, Petrenko OI.  Evolution of insulin genes and their introns.  Folia Biol 1984;30 Spec No:65-71

7) Kashuba VI, Kavsan VM, Petrenko AI, Dmitrenko VV, Koval AP.  Allelic polymorphism of the chum salmon preproinsulin gene. [Article in Russian] Mol Biol (Mosk) 1986;20:845-852.

8) Koval AP, Petrenko AI, Kavsan VM.  Structure of the 5’-flanking region of the cloned salmon preproinsulin gene.  [Article in Russian]  Dokl Akad Nauk SSSR 1988;301(3):746-749.

9) KovalAP, Petrenko AI, Dmitrenko VV, Kavsan VM.  Nucleotide sequence of chum salmon preproinsulin gene.  [Article in Russian]  Mol Biol (Mosk) 1989 Mar;23(2):473-480.

10) Koval AP, Petrenko AI, Kavsan VM.  Sequence of the salmon (Oncorhynchus keta) [corrected] preproinsulin gene.  Nucleic Acids Res 1989 Feb 25;17(4):1758.

11) Strokovskaya L, Kikhno IM, Veselovskij OV, Skuratovskaja IN, Mirjuta NY, Petrenko A, Solomko AP.  Malacosoma neustria nuclear polyhedrosis virus-based expression vector.  [Article in Russian]  Biopolymeri I Kletka 1990, 6:83-89.

12) Sokol-Misiak W, Markiewicz WT, Szydlowska B, Petrenko A.  Introduction of the glucocorticoid binding sequences into the expresion vector pdelta SVE-CAT and its  effect on the CAT gene expression in mammalian cells.  Acta Biochem Pol 1991;38(1):17-24.

13) Kavsan V, Koval A, Petrenko O, Roberts CT Jr, LeRoith D.  Two insulin genes are present in the salmon genome.  Biochem Biophys Res Commun 1993 Mar 31;191(3):1373-1378.

14) Petrenko A, Strokovskaja LI, Solomko AP.  Nucleotide sequence of MnNPV poyhedrin gene. [Article in Russian] Biopolimeri I kletka 1994; 10(3-4):105.

15) Petrenko O, Ischenko I, Enrietto PJ.  Isolation of a cDNA encoding a novel chicken chemokine homologous to mammalian macrophage inflammatory protein-1 beta.  Gene 1995 Jul 28;160(2):305-306.

16) Chaschina LI, Petrenko A, Vagina IN, Krysan KV, Solomko AP.  Structural modifications of plasmid pATV8 DNA in transgenic mice: 1. Structural analysis of integrated transgenome and biological effects of transgenesis. [Article in Russian]  Biopolimeri I kletka 1997; 13(4):323-327.

17) Petrenko O, Ischenko I, Enrietto PJ.  Characterization of changes in gene expression associated with malignant transformation by the NF-kappaB family member, v-Rel.  Oncogene 1997 Oct 2;15(14):1671-1680.

18) Zurovec M, Petrenko O, Roll R, Enrietto PJ.  A chicken c-Rel-estrogen receptor chimeric protein shows conditional nuclear localization, DNA binding, transformation, and transcriptional activation.  Oncogene 1998 June 18; 16(24):3133-3142.

19) Petrenko O, Beavis A, Klaine M, Kittappa R, Godin I, Lemischka IR.  The molecular characterization of the fetal stem cell marker AA4.  Immunity 1999 June 24; 10(6):691-700.

20) Nikiforov MA, Kotenko I, Petrenko O, Beavis A, Valenick L, Lemischka I, Cole MD.  Complementation of Myc-dependent cell proliferation by cDNA expression library screening.  Oncogene. 2000 Oct 5; 19(42):4828-31.

21) Nikiforov MA, Chandriani S, O'Connell B, Petrenko O, Kotenko I, Beavis A, Sedivy JM, Cole MD. A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism. Mol Cell Biol. 2002 Aug; 22(16):5793-800.

22) Petrenko O, Fingerle-Rowson G, Peng T, Mitchell RA, Metz CN. Macrophage migration inhibitory factor deficiency is associated with altered cell growth and reduced susceptibility to Ras-mediated transformation.
J Biol Chem. 2003 Mar 28; 278(13):11078-85.

23) Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P, Moll UM. p53 has a direct apoptogenic role at the mitochondria. Mol Cell. 2003 Mar; 11(3):577-90.

24) Fingerle-Rowson G, Petrenko O, Metz CN, Forsthuber TG, Mitchell R, Huss R, Moll U, Muller W, Bucala R. The p53-dependent effects of macrophage migration inhibitory factor MIF revealed by gene targeting. Proc Natl Acad Sci U S A. 2003 Aug 5; 100(16):9354-9.

25) Petrenko O, Zaika A, Moll UM. deltaNp73 facilitates cell immortalization and cooperates with oncogenic Ras in cellular transformation in vivo. Mol Cell Biol. 2003 Aug; 23(16):5540-55.

26) Ischenko I, Petrenko O, Gu H, Hayman MJ. The scaffolding protein Gab2 mediates fibroblast
transformation by the Sea tyrosine kinase. Oncogene. 2003 Sep; 22(41):6311-8.

27) Mihara M, Erster S, Kim R, Petrenko O and Moll UM. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that precedes p53 target gene activation. Mol Cell Biol. 2003. Submitted.

28) Moll U, Petrenko O. The MDM2-p53 interaction. Review. Molecular Cancer Research 2003. In press.

29) Petrenko O and U Moll. Macrophage migration inhibitory factor MIF interferes with the Rb-E2F pathway. Mol Cell Biol. 2003. Submitted