Antonius Koller, Ph.D., Research Assistant Professor.

Antonius Koller, Ph.D.
Technical Director, Proteomics Center
Research Assistant Professor, Pathology
Stony Brook University Medical Center
BST9, Rm. 168A
Stony Brook, NY 11794-8691
Tel: 631-444-6553
Fax: 631-444-3285
Email: koller@osa.sunysb.edu
Education:
| 1990 | M.S., Biochemistry, Biozentrum of the University of Basel, Switzerland |
| 1994 | Ph.D., Biochemistry, Biozentrum of the University of Basel, Switzerland |
Postdoctoral and Professional Training:
| 1995-2000 | Postdoctoral Fellow, Biology Department, University of California, San Diego, CA |
| 2000-03 | Staff Scientist/Senior Staff Scientist, Proteomics, Torrey Mesa Research Institute, La Jolla, CA |
| 2003-05 | Senior Staff Scientist, Proteomics, Diversa Corporation, San Diego, CA |
| 2005-07 | Research Specialist III, Howard Hughes Medical Institute, University of California, San Diego, CA |
Research Summary:
Dr. Koller is the Technical Director of the Proteomics Center at the School of Medicine. The Proteomics Center provides a protein discovery platform for researchers at the University. There are three components to the SBU proteomics facility: (1) protein extraction from cell lines and tissues; (2) sample analysis by gel electrophoresis or mass spectrometry-based shotgun proteomics; (3) tandem mass spectra analysis, protein quantification, and data mining.
Proteomics Publications:
Alto, N. M. A. W. Weflen, M. J. Rardin, D. Yarar, C. S. Lazar, R. Tonikian, A. Koller, S. S. Taylor, C. Boone, S. S. Sidhu, S. L. Schmid, G. A. Hecht and J. E. Dixon. 2007. The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. J. Cell Biol., 178:1265-1278.
Navarro, L., A. Koller, R. Nordfelth, H. Wolf-Watz, S. Taylor and J. E. Dixon. 2007. Identification of a molecular target for the Yersinia protein kinase A. Mol. Cell, 26:465-477.
Schauble, S, C. C. King, M. Darshi, A. Koller, K. Shah and S. S. Taylor. 2007. Identification of ChChd3 as a novel substrate of the cAMP-dependent protein kinase (PKA) using an analog-sensitive catalytic subunit. J. Biol. Chem., 282:14952-14959.
Koller, A, J. Khandurina, J. Li, J. Kreps, D. Schieltz and A. Guttman. 2004. Analysis of high-mannose-type oligosaccharides by micro-liquid chromatography-mass spectrometry and capillary electrophoresis. Electrophoresis, 25:2003-2009.
Balmer, Y., A. Koller, G. del Val, P. Schürmann and B. B. Buchanan. 2003. Proteomics Uncovers Proteins Interacting Electrostatically with Thioredoxin in Chloroplasts. Photosynthesis Research, 79:275-280.
Washburn M. P., A. Koller, G. Oshiro, R. R. Ulaszek, D. Plouffe, C. Deciu, E. Winzeler and J. R. Yates 3rd. 2003. Protein pathway and complex clustering of correlated mRNA and protein expression analyses in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA, 100:3107-3112.
Balmer, Y., A. Koller, G. del Val, W. Manieri, P. Schürmann and B. B. Buchanan. 2003. Proteomics gives insight into the regulatory function of chloroplast thioredoxins. Proc. Natl. Acad. Sci. USA, 100:370-375.
Hunter, T.C., N. L. Andon, A. Koller, J. R. Yates 3rd and P. A. Haynes. 2002. Functional proteomics toolbox: methods and applications. Journal of Chromatography B, 782:165-81.
Andon, N. L., S. Hollingworth, A. Koller, A.J. Greenland, J.R. Yates 3rd and P. A. Haynes. 2002. Proteomic characterization of wheat amyloplasts using identification of proteins by tandem mass spectrometry. Proteomics 2:1156-68.
Koller, A, M. P. Washburn, B. M. Lange, N. L. Andon, C. Deciu, P. A. Haynes, L. Hays, D. Schieltz, R. Ulaszek, J. Wei, D. Wolters and J.R. Yates 3rd. 2002. Proteomic survey of metabolic pathways in rice. Proc. Natl. Acad. Sci. USA, 99: 11969-11974. (Accompanied by a PNAS Editorial Commentary: Plant proteomics: BLASTing out of a MudPIT. PNAS 99:11564-11566).
