Stony Brook University | School of Medicine | Health Sciences Center
Antonius Koller, PhD
Antonius Koller, PhD
Technical Director, Proteomics Center
Research Assistant Professor, Pathology
Basic Science Tower, Level 9
Stony Brook Medicine
Stony Brook, NY 11794-8691
Tel: (631) 444-6553
Fax: (631) 444-3285
Email: koller@osa.sunysb.edu
Research Summary:
Dr.
Koller is the Technical Director of the Proteomics Center at the School
of Medicine. The Proteomics Center provides a protein discovery
platform for researchers at the University. There are three components
to the SBU proteomics facility: (1) protein extraction from cell lines
and tissues; (2) sample analysis by gel electrophoresis or mass
spectrometry-based shotgun proteomics; (3) tandem mass spectra analysis,
protein quantification, and data mining.
| Education: | |
| 1990 | M.S., Biochemistry, Biozentrum of the University of Basel, Switzerland |
| 1994 | Ph.D., Biochemistry, Biozentrum of the University of Basel, Switzerland |
| Positions and Employment: | |
| 1995-00 | Postdoctoral Fellow, Biology Dept, University of California, CA |
| 2000-03 | Staff Scientist/Senior Staff Scientist, Proteomics, Torrey Mesa Research Institute, CA |
| 2003-05 | Senior Staff Scientist, Proteomics, Diversa Corporation, CA |
| 2005-07 | Research Specialist III, Howard Hughes Medical Institute, University of California, CA |
Proteomics Publications:
Alto, N. M. A. W. Weflen, M. J. Rardin, D. Yarar, C. S. Lazar, R. Tonikian, A. Koller, S. S. Taylor, C. Boone, S. S. Sidhu, S. L. Schmid, G. A. Hecht and J. E. Dixon. 2007. The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. J. Cell Biol., 178:1265-1278.
Navarro, L., A. Koller, R. Nordfelth, H. Wolf-Watz, S. Taylor and J. E. Dixon. 2007. Identification of a molecular target for the Yersinia protein kinase A. Mol. Cell, 26:465-477.
Schauble, S, C. C. King, M. Darshi, A. Koller, K. Shah and S. S. Taylor. 2007. Identification of ChChd3 as a novel substrate of the cAMP-dependent protein kinase (PKA) using an analog-sensitive catalytic subunit. J. Biol. Chem., 282:14952-14959.
Koller, A, J. Khandurina, J. Li, J. Kreps, D. Schieltz and A. Guttman. 2004. Analysis of high-mannose-type oligosaccharides by micro-liquid chromatography-mass spectrometry and capillary electrophoresis. Electrophoresis, 25:2003-2009.
Balmer, Y., A. Koller, G. del Val, P. Schürmann and B. B. Buchanan. 2003. Proteomics Uncovers Proteins Interacting Electrostatically with Thioredoxin in Chloroplasts. Photosynthesis Research, 79:275-280.
Washburn M. P., A. Koller, G. Oshiro, R. R. Ulaszek, D. Plouffe, C. Deciu, E. Winzeler and J. R. Yates 3rd. 2003. Protein pathway and complex clustering of correlated mRNA and protein expression analyses in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA, 100:3107-3112.
Balmer, Y., A. Koller, G. del Val, W. Manieri, P. Schürmann and B. B. Buchanan. 2003. Proteomics gives insight into the regulatory function of chloroplast thioredoxins. Proc. Natl. Acad. Sci. USA, 100:370-375.
Hunter, T.C., N. L. Andon, A. Koller, J. R. Yates 3rd and P. A. Haynes. 2002. Functional proteomics toolbox: methods and applications. Journal of Chromatography B, 782:165-81.
Andon, N. L., S. Hollingworth, A. Koller, A.J. Greenland, J.R. Yates 3rd and P. A. Haynes. 2002. Proteomic characterization of wheat amyloplasts using identification of proteins by tandem mass spectrometry. Proteomics 2:1156-68.
Koller, A, M. P. Washburn, B. M. Lange, N. L. Andon, C. Deciu, P. A. Haynes, L. Hays, D. Schieltz, R. Ulaszek, J. Wei, D. Wolters and J.R. Yates 3rd. 2002. Proteomic survey of metabolic pathways in rice. Proc. Natl. Acad. Sci. USA, 99: 11969-11974. (Accompanied by a PNAS Editorial Commentary: Plant proteomics: BLASTing out of a MudPIT. PNAS 99:11564-11566).
