Emily Chen, PhD

Emily Chen, PhD
Assistant Professor
   
Departments of Pharmacology & Pathology
Proteomics Core Laboratory

Stony Brook Medicine
Stony Brook, NY 11794-8651


Tel: (631) 444-3134
Email: emily@pharm.stonybrook.edu

Research Summary:
Dr. Chen is specialized in using a mass spectrometry-based proteomic approach to analyze complex protein mixtures. Her primary interest is to apply her proteomic expertise in identifying determinants of organ-specific breast cancer metastasis. Using the experimental metastasis model, she found changes in the tumorgenecity of the cancer cells that successfully proliferate at sites of metastasis. Specifically, the genes and proteins expressed in those cells differ in part from those expressed by primary tumor cells. Moreover, the changes in expression differ accordingly to the individual metastatic site. These data indicate that the tumor cells are selected for or adapt to the new environments by initiating a unique program of transcriptional and translational regulation.

Education:      
Institute and Location Degree Year(s) Field of Study
University of California, San Diego B.S. 1994-97 Biology
University of California, San Diego Ph.D. 1997-02  Molecular Pathology
Postdoctoral Training:
2002-03
Postdoctoral fellow: Dr. Carlos F. Barbas III’s Lab at the Scripps Research Institute, CA
2003-04
Postdoctoral fellow: Dr. Felding-Habermann’s Lab at the Scripps Research Institute, CA
2004-07 Postdoctoral fellow: Dr. John R. Yates III’s Lab at the Scripps Research Institute, CA
Honors:
1997-98 Fellowship from the Graduate Program of Molecular Pathology at UCSD School of Medicine
1998-02 Pre-doctoral U.S. Army Breast Cancer Fellowship
2003 Clinical Research Feasibility Funding Award (CreFF)
2003-04 NIH post-doctoral training Fellowship
2004 AACR-WICR Brigid G. Leventhal Scholar Award
2005 Susan G. Komen Breast Cancer Foundation Travel Award

Peer Reviewed Publications: