Gang Xie, Ph.D.

Gang Xie
Post Doctorial Associate
e-mail: Gang.Xie@stonybrookmedicine.edu

Dr. Xie received his BS in Biochemistry from Nanjing University, China and his PhD in Chemistry from South Dakota State Univerity.   His research includes understanding the heme acquisition process in human pathogen Staphylococcus aureus at a molecular level and its role in pathogenesis and analyzing the effect of plant-derived polysaccharides on macrophage and neutrophil functions.  Dr. Xie is currently working on the metabolism and pharmacokinetics of novel anticancer agents under study in our lab.

Selectected Peer-Reviewed Publications:

1.  Schepetkin IA, Xie G, Jutila M and Quinn MT.  2009 Complement-fixing activity of      humic substances from Shailajit and other natural sources.  Phytotherapy Research, 23:373-384.
       To view pdf click here

2.    Xie G, Liu M. Zhu H. and Lei B. 2008 Esterase of Streptococcus equi, SeE, is a

      novel nonspecific carboxylic ester hydrolase.  FEMS Microbiology letters,

      289(2):181-6.

        To view pdf click here.

3.    Zhu H, Xie G, Liu M, Olson JS, fabian M. dooley DM, and Lei B. 2008.  Pathway

       for heme uptake from human methemoglobin by the Iron-Regulated Surface

       Determinants (Isd) system of Staphyloccoccus aureus.  Journal of Biological

       Chemistry, 283:18450-18460.

         To view pdf click here.

4.    Xie G, Schepetkin IA, Siemsen DW, Kirpotina LN, Wiley JA, Quinn MT.  2008

       Fractionation and characterization of biologically-active polysaccharides from

       Artemisia tripartita.  Phytochemistry, 69(6):1359-71

         To view pdf click here.

5.    Schepetkin IA, XIE G, Kirpotina LN, Klein RA, Jutila MA, Quinn MT. 2008

       Macrophage immunomodulatory activity of polysaccharides isolated from

       Opuntia polyacantha.  International Immunopharmacology, 8(10):1455-66.

         To view pdf click here.

6.     Xie G, Schepetkin IA, Quinn MT. 2007.  Immunomodulatory activity of acidic

        polysaccharides isolated from Tanacetum vulgare.  L. International

        Immunopharmacology, 7(13):1639-50.

           To view pdf click here.

7.       Xie G,and West TP.  2006.  citric acid production by Aspergillus niger on wet

          corm distillers grains.  Letters in Applied Microbiology, 43.269-273